Kane, Bellingham and Foden are unable to play together - does the manager have a point?
With six wins in six games, an unbreached defense and World Cup qualification confirmed with matches remaining, Three Lions boss Thomas Tuchel can argue he has got all of his big qualifying decisions correct.
However, in the lead-up to Thursday's Wembley encounter against Serbia, he raised questions when he said that three of the England's elite footballers - Jude Bellingham, Phil Foden and Harry Kane - struggle to perform in the equivalent formation.
"Presently, if we keep the structure, they are unable to feature.
"It's possible but not within this system, not for the balance that we established and not in this formation that comes also with wingers who are highly specialized in their positions. We play at the moment with specific numbered positions."
From automatic picks to contested places
England's creative talents have been utilized out wide for England in the past, but his team selections suggest that the Barcelona loanee and Arsenal's winger are his first choices on the left and right flank respectively.
The question remains whether Bellingham, Foden and Kane play together?
Former Three Lions boss certainly thought so.
Bellingham, Foden and Kane started all of England's seven games at last summer's tournament in Germany, where Southgate's side were defeated by Spain in the final.
In the 16 matches the three have featured alongside each other, England have secured 10 victories, shared points three times and lost three, scoring 36 times and letting in 14 strikes.
Strategic view: Versatile Foden offers solutions
Tuchel has played a 4-2-3-1 system that changes shape when England attack.
The Aston Villa player has been the primary attacking midfielder because of his strong ball-carrying, shooting ability and ability to attack the box when the forward retreats.
Tuchel has mentioned preferring natural flank operators. Saka and Gordon consistently operate in wide areas and can hold the ball well, engage in one-on-one situations, and enter the area to finish.
Supporting the attacking quartet, Tuchel utilizes two central midfielders consisting of a holding midfielder and another with greater freedom to contribute to the attack.
What solutions exist for the trio?
Foden and Bellingham would be battling with other creative midfielders for the creative hub, with Kane expected to lead up front.
Foden could play as the number nine, which in theory could enable both Bellingham and Foden to feature instead of Kane.
There is a potential solution all three could coexist effectively and Tuchel hinted at it this week.
"For Man City, he plays almost like a central or attacking midfielder, so perhaps in coming months we regard him as a central midfielder," he said.
Foden has been utilized as a flexible midfielder this season.
That has enabled him to operate from deeper areas and could categorize him as the number eight, alongside a holding midfielder.
This would then enable Bellingham to operate as the attacking midfielder and Kane as the striker.
No matter whether Tuchel chooses to configure the team like this at the global tournament, what seems encouraging is his willingness to leave big players out in the name of balance.